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Novartis acquires GSK’s cancer drug assets for $14.5bn up front

Executive Summary

Essentially ending its quest to be a leading oncology company, GlaxoSmithKline PLC divested to Novartis AG several cancer assets for $14.5bn up front, plus a $1.5bn development milestone dependent upon the results (specifically the achievement of a survival endpoint) in COMBI-d, a Phase III trial comparing the combination of dabrafenib (the BRAF inhibitor Tafinlar) and trametinib (the MEK inhibitor Mekinist) with dabrafenib alone in patients with stage IIIC or metastatic (stage IV) BRAF V600E/K mutation-positive cutaneous melanoma.
Deal Industry
  • Pharmaceuticals
Deal Status
  • Final
Deal Type
  • Acquisition
    • Full Acquisition
    • Payment Includes Cash
    • Includes Earnout

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