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Executive Summary

In Vivo summarizes the technologies of several recently founded companies: Spun out of London's Imperial College School of Medicine in July, Circassia Ltd. will develop treatments for cat-induced asthma and allergies. Copharos Inc., was formed in August 2000 to develop Vitamin B12-based radioactive imaging and therapeutic agents for the early detection and treatment of breast, lung and other cancers. EyeTech Pharmaceuticals Inc., founded in April 2000, has embarked on Phase IB trials for its drug for wet macular degeneration, a leading cause of adult-onset blindness. Invenux Inc. will use its Evolutionary Chemistry integrated discovery system to identify antibiotic compounds effective against drug-resistant organisms as well as discover drugs with broad-spectrum antibiotic activity. Sensatex/Lifelink Inc. will provide wireless, remote health care monitoring with its Smart Shirt, a special fabric interwoven with sensors that continuously relays information on a patient's vital signs. Sensory Technologies Inc. was formed in November 1999 to commercialize sensory-enhancement research of James Collins, PhD at Boston University's Center for Biodynamics.

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