When is a Target Not a Target?
Medarex is reevaluating its plans to bring 10 antibodies into the clinic each year, in part because targets identified by its array of young partners are taking a lot of work to validate. The company has gained appreciation for vaccines and for the potential of using antibodies as general immune stimulants rather than specifically targeted therapeutics.
You may also be interested in...
The process of hunting for drugs is now markedly different than it was a few decades ago, partly because research organizations are much bigger and market pressures more intense. Technology has catalyzed the biggest shifts, decreasing the role of individuals and putting more emphasis on method than conceptualization. But the high-tech methods haven't been as productive as expected, and so research executives are increasingly considering which of the traditional ways might be worth recapturing.
A cluster of recent deals indicates just how hot antibodies are right now, and also hints at some old difficulties and new opportunities in the field.
American Injectables plans to build up its US-based manufacturing after securing a commitment for $10m of ‘Series A’ financing from New Rhein Healthcare Investors, which it will use to scale up production and launch several generic parenteral products.