Company Changes (12/03)

ALEXANDER W. James, MD

To: Pozen Inc., SVP, Product Dev.(Nov.)

From: Pharma Research Corp., Pres. & Chief Medical Officer

Tel: [phone]

ALLENDER, William

To: Cytomedix Inc., CFO(Dec.)

From: Selkirk LLC, Sr. Analyst

Tel: [phone]

ARTHUR, Bill

To: SpectRx Inc., Pres. & COO(Nov.)

From: MiniMed Inc., VP, Sales

Tel: [phone]

BARCLAY, Bruce J.

To: SurModics Inc., Pres. & COO(Dec.)

From: Vascular Architects Inc., Pres. & CEO

Tel: [phone]

BORENSTEIN, Raphaela

To: Celmed BioSciences Inc., VP, Reg. Affairs & Product Strategy(Nov.)

From: Theratechnologies Inc., VP, Reg. & Clinical Affairs

Tel: [phone]

CAUDRELIER, Pierre A.

To: Celmed BioSciences Inc., VP, Clinical Affairs(Nov.)

From: IDM Biotech, VP, Scientific & Medical Affairs & General Mgr., IDM

Biotech Ltd.

Tel: [phone]

CLINE, Mark E.

To: Cytomedix Inc., Pres.(Dec.)

From: Diversified Corp. Resources Inc., BOD & BOD, River Ranch Child Educational Charities

Tel: [phone]

COSTANZO, Santino

To: Organogenesis Inc., VP, Sales(Dec.)

From: Novartis Pharmaceuticals Corp., Dir., Sales & Mktg.

Tel: [phone]

GOODING, Doug

To: Regado BioSciences, Pres. & Venture Partner, The Aurora Funds(Nov.)

From: The Aurora Funds, Principal

Tel: [phone]

HOOS, Anton, MD

To: Altus Biologics Inc., VP, Pharmaceutical Dev.(Sep.)

From: Aventis Behring LLC, VP, Global Project & Life Cycle Mgmt.

Tel: [phone]

KRAUS, Al

To: RenalTech International LLC, Pres. & CEO(Aug.)

From: NOvoVascular Inc., Pres. & CEO

Tel: [phone]

LEIMER, Axel H.

To: vectron therapeutics AG, CBO(Sep.)

From: Source Precision Medicine GMBH, Managing Dir. & Investment Advisor, Future Capital AG

Tel: [phone]

LICHTWARDT, Gregory E.

To: Conceptus Inc., EVP, CFO & Treasurer(Nov.)

From: InnoVentry Inc., EVP, Fin., CFO & Corp. Secretary

Tel: [phone]

Executive Recruiter: Korn/Ferry International

MacKAY, Geoff

To: Organogenesis Inc., CEO(Dec.)

From: Novartis Pharma Canada, VP & Head, Immunology & Transplantation

Bus. Unit

Tel: [phone]

MARTIN, David W., Jr., MD

To: GangaGen Inc., Chmn. & CEO(Nov.)

From: Eos Biotechnology Inc., CEO

Tel: [phone]

MATHERS, Thomas P.

To: Peptimmune Inc., Pres.(Nov.)

From: Cell Based Delivery, Pres. & CEO

Tel: [phone]

MAZA, Elliot M.

To: Emisphere Technologies Inc., CFO(Dec.)

From: Ernst & Young LLP, Partner, Transaction Advisory Services

Tel: [phone]

MIDDLEBROOK, Robert

To: Perlegen Sciences Inc., Chief Corp. Dev. Officer(Nov.)

From: Fidelity Investments, SVP

Tel: [phone]

OPENSHAW, Ronald

To: Pharmagene PLC, EVP, Corp. Dev.(Nov.)

From: WestLB Panmure, Exec. Dir., Life Sciences Group

Tel: [phone]

PINNOLA, Richard M.

To: LipoScience Inc., COO(Nov.)

From: TriPath Imaging Inc., VP, Mktg. & Commercial Dev.

Tel: [phone]

POST, Claes

To: Gastrotech Pharma AS, CEO(Nov.)

From: Karolinska Institute, Prof., Neuropharmacology

Tel: [phone]

PUCHOIS, Pascal, PhD

To: Celmed BioSciences Inc., VP, Preclinical Research & Technologies(Nov.)

From: Bio-Inova Life Sciences International, Acting CEO

Tel: [phone]

SCHOENECK, James A.

To: ActivX Biosciences Inc., CEO(Nov.)

From: Prometheus Laboratories Inc., Pres. & CEO

Tel: [phone]

Executive Recruiter: TMP/Highland Partners

STEAD, Richard B., MD

To: Nephros Therapeutics Inc., Chief Medical Officer(Nov.)

From: Immunex Corp., VP, Clinical R&D

Tel: [phone]

STRACEY, Robin C.

To: Applied Imaging Corp., Pres. & COO(Nov.)

From: Thermo Electron Corp., VP & General Mgr., Chromatology & Mass Spectrometry Bus. Unit

Tel: [phone]

WIESINGER, Lyn

To: Vicuron Pharmaceuticals Inc., SVP, Mktg. & Market Dev.(Nov.)

From: Bristol-Myers Squibb Co., Head, Global Anti-Infective Mktg.

Tel: [phone]

Executive Recruiter: Russell Reynolds Associates Inc.

WOKER, Mathias

To: Graffinity Pharmaceuticals AG, VP, US Bus. Dev.(Oct.)

From: Spherics Inc., VP, Bus. Dev.

Tel: [phone]

WUELFROTH, Petra, PhD

To: vectron therapeutics AG, CEO(Sep.)

From: Consultant

Tel: [phone]

WUURMAN, Bart

To: De Novo Pharmaceuticals Ltd., CEO(Nov.)

From: Antisoma PLC, Dir., Bus. Dev.

Tel: [phone]