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Start-Up Previews (02/07)

Executive Summary

A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group: Spine Devices: Looking for a Twist Rather than a Tweaks, features profiles of CoreSpine, Interventional Spine, and Paradigm Spine. Plus these Start-Ups Across Health Care: Claros Diagnostics, Cure Therapeutics, Enigma Diagnosics, Generic Medical Devices, and Nitec Pharma.

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Enigma Diagnostics Ltd.

The key to combating an infectious disease threat, be it an individual case of Chlamydia or the global threat of bioterrorism or pandemic avian flu, is rapid on-site diagnosis, enabling physicians to treat--or public health professionals to contain--the disease. One solution is the use of the gold standard test for biological agents, real-time polymerase chain reaction testing. Enigma Diagnostics Ltd. says it is the first UK company to take this technique out of the laboratory and into the field.

Generic Medical Devices Inc.

Can generics, which have had a significant impact on the pharma market, make a similar dent in the medtech world? Generic Medical Devices intends to find out. It will manufacture and sell generic versions of off-patent devices that have become the gold standard in their respective indications. Expedited regulatory, reimbursement and marketing will enable GMD to price its products at a substantial discount to their branded counterparts.

Claros Diagnostics Inc.

A point-of-care diagnostic instrument that had the advantages of a test strip device in terms of ease-of-use and rapid results along with ELISA-like capabilities for major diseases would make diagnosis routine within the course of a patient visit and would revolutionize diagnostic practices. Claros Diagnostics has developed just such a device which it hopes to sell to doctors' offices, initially for urological applications, beginning in 2009.

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