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Start-Up Previews (04/2008)

Executive Summary

A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, "Nanotechnology, a Balm for the Challenges of Drug Delivery," features profiles of BIND Biosciences, Liquidia Technologies, Nanolymf, Tempo Pharmaceuticals, and TransGenex Nanobiotech. Plus these Start-Ups Across Health Care: Breathe Technologies, Crospon, and InterMed Discovery.

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Breathe Technologies Inc.

The developers of a miniature, wearable ventilator for people with severe respiratory disorders view their product as the iPod of ventilators. Breathe Technologies aims to commercialize the first truly ambulatory ventilator. The company believes its innovative technology will fill an unmet need for patients with severe ventilatory insufficiency, both in the hospital setting and in the home.

Crospon Ltd.

New imaging technology employed through a therapeutic endoscope provides the most relevant information to diagnose gastroesophageal reflux disease (GERD), according to its manufacturer, Crospon. Furthermore, the Irish start-up says its novel EndoFLIP (endoscopic functional lumen imaging probe) technology can be used to assist in GERD surgeries and to assess the results.

Liquidia Technologies Inc.

Liquidia Technologies is developing nanoparticles whose size, shape, particle cargo, and target specificity can be exquisitely controlled. In order to create its particles, Liquidia borrows fabrication methods originally developed by the electronics industry. I

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