In Vivo is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction
UsernamePublicRestriction

Start-Up Previews

Executive Summary

A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, "Start-Ups Against Inflammation," features profiles of Asphleia Pharmaceuticals, Calistoga Pharmaceuticals, ProtAb Ltd., and Resolvyx Pharmaceuticals. Plus these Start-Ups Across Health Care: CG Therapeutics, Healionics, Mpathy Medical Devices and Pronostics.

You may also be interested in...



Resolvyx Pharmaceuticals Inc.

Resolvyx Pharmaceuticals is developing a new class of lipid mediators, dubbed resolvins, which are generated through the oxidation of the omega-3 fatty acids EPA and DHA. Although omega-3 fatty acids have long been heralded for their reputed ability to reduce inflammation, many grams of omega-3 fatty acids have to be consumed to produce any physiological effect. In contrast, Resolvyx says its resolvins are potent at low milligram quantities and so are good candidates for commercialization as drugs. Resolvyx is advancing two programs into the clinic.

Asphelia Pharmaceuticals Inc.

In an era of high-tech medicine, of painstakingly designed molecular inhibitors and personalized medicine driven by genetic responses to drugs, Asphelia Pharmaceuticals is placing its bets on a primitive technology: intestinal worms, known as helminthes. Helminthes release proteins that boost the activity of regulatory T-cells, and the antigens they produce appear to influence a variety of targets. Asphelia is developing helminthes as an oral treatment for Crohn's and other autoimmune diseases. Also in the company's pipeline, a novel oral compound that targets integrins in order to treat immunological and inflammatory disorders.

CG Therapeutics Inc.

It sometimes happens that a medicine developed for one purpose is discovered to work wonderfully well in other, initially unanticipated indications. The founders of CG Therapeutics believe they can benefit from just such serendipity. The start-up company is developing a molecule first pursued at Ohio State University as a long-acting contraceptive some 30 years ago, now as a cancer vaccine meant to treat solid tumors.

Related Content

Related Companies

UsernamePublicRestriction

Register

OM014142

Ask The Analyst

Ask the Analyst is free for subscribers.  Submit your question and one of our analysts will be in touch.

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel