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Start-Up Previews (11/2010)

Executive Summary

A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, "Start-Ups Look For A Place In Coming Hepatitis C Combo Regimens." features profiles of AiCuris, Avila Therapeutics, Okairos, Viroblock and Zirus. Plus these Start-Ups Across Health Care: Arineta, HemoShear, Hygieia and Silver Bullet Therapeutics.

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Hygieia Inc.

An urgent need exists for a simple and cost-effective way to support insulin therapy, mainly for people with type 2 diabetes, in between physician check-ups. Hygieia Inc. plans on addressing this need in a big way with its patient- and clinician-friendly Diabetes Insulin Guidance System (DIGS), designed to replace commonly used glucose meters that simply provide blood sugar readings. Hygieia's DIGS device is designed to support diabetes patients' glycemic control by providing them with with simple dose-by-dose insulin recommendations.

Arineta Ltd.

Instead of relying on a conventional whole-body computed tomography scan in a hospital setting for cardiac imaging, cardiologists could someday have a smaller, lighter and less expensive CT system in their own office. Israeli-based Arineta Ltd. is developing just such a dedicated cardiovascular CT device.

AiCuris GMBH & Co. KG

With seven molecules in clinical development, another three preclinical compounds approaching the clinic, and a half-dozen discovery programs divided equally between virology and bacteriology, AiCuris is seeking the keys to thwarting viral replication. The start-up has drug candidates targeting herpes simplex virus, human cytomegalovirus and hepatitis C.

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