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Start-Up Previews, October 2013

Executive Summary

This Month's Profile Group: Biotechs Share Endocrine Enthusiasm, features profiles of Atterocor, Crinetics Pharmaceuticals, and OctreoPharm Sciences. Plus these Start-Ups Across Health Care: Biom’Up SA, KemPharm, LIM Innovations, Reflectance Medical, and Trino Therapeutics.

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Reflectance Medical Inc.

Trauma patients who have internal bleeding or are in shock are administered either IV fluid or blood, but the necessary volume of fluid replacement can’t be determined until blood samples are analyzed for metabolic parameters. Reflectance Medical Inc. has developed a noninvasive monitor that combines a muscle oxygen saturation (SmO2) and muscle pH (pHm) sensor to determine optimal replacement volumes in real time.

LIM Innovations Inc.

People living with a lower limb amputation have less-than-desirable prosthetic device options to help regain mobility and independence – available prosthetics are costly, uncomfortable, not adjustable, take weeks to make as they are hand-fabricated, require multiple office visits with a prosthetist, and need to be replaced about every three years. LIM Innovations Inc. hopes to improve amputees’ lives with a prosthetic socket that can be mass-manufactured and then assembled to fit and mold to each patient, and to be remolded over time.

Biom’Up SA

Biom’Up SA has developed an abdominal wall reinforcement implant designed specifically for laparoscopic hernia repair. Covamesh is made from proprietary biopolymers that the company thinks allow for better integration into the abdominal wall, easier insertion, and adhesion prevention during the healing process.


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