New Keytruda Approval Rekindles An Old Debate
Approval for first-line BRAF+ patients puts Merck's Keytruda ahead of Bristol's Opdivo in melanoma, and in line to take share from BRAF/MEK combos, which are currently dominant in this patient population. Interactive timeline gives visual overview of immunotherapy approvals in key markets.
You may also be interested in...
New FDA labeling brings Tafinlar/Mekinist into adjuvant melanoma setting, but Bristol's competing Opdivo already has captured nearly 50% of the market and is approved regardless of genetic mutation.
Bristol's Opdivo and Novartis/GlaxoSmithKline's Tafinlar/Mekinist combo both performed well in early, post-surgical treatment of advanced melanoma in trials reported at ESMO, promising yet another revolution in the standard of care, but leaving Roche's Zelboraf/Cotellic in the dust.
Execs speculated during third-quarter earnings calls about the impact of FDA approval for Merck's Keytruda in first-line lung cancer and looked forward to readouts of combination studies, which could soon bring another market shake-up.