In Vivo is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By


Mitsubishi licenses Neurocrine movement disorders drug

This article was originally published in Scrip

Executive Summary

Mitsubishi Tanabe has licensed the development and commercialization rights in Japan and other Asian markets for Neurocrine Biosciences' VMAT2 inhibitor, NBI-98854. Initially, Mitsubishi Tanabe will develop NBI-98854 in Japan for the chorea associated with Huntington's disease and tardive dyskinesia. Neurocrine will receive an initial payment of $30m and is eligible to receive up to $85m in additional milestone payments associated with the development and commercialization of NBI-98854 in Asia. It will also receive royalties on product sales in the relevant markets. The vesicular monoamine transporter 2 inhibitor product is already in Phase III tardive dyskinesia. It is designed to regulate levels of dopamine release during nerve communication but with fewer off-target side-effects. In addition to Japan, Mitsubishi Tanabe's territory also includes China, South Korea, Philippines, Indonesia, Taiwan, Singapore, Malaysia, Thailand, and Hong Kong. Neurocrine retains full commercial rights to NBI-98854 in North America, Europe and other countries outside of Asia.



Related Companies




Ask The Analyst

Ask the Analyst is free for subscribers.  Submit your question and one of our analysts will be in touch.

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts