Principal Analyst, Datamonitor Healthcare
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Latest From Amanda Micklus
Device fundraising in the fourth quarter totaled $1.5bn, a 42% decrease from Q3's $2.6bn. Q4 M&A activity reached $8.6bn. Q4 diagnostics financings brought in $1.2bn (a 32% increase over Q3) and M&As totaled $1.3bn (the second-highest quarter of the year).
Derived from Strategic Transactions, Informa’s premium source for tracking life sciences deal activity, the Dealmaking column is a survey of recent health care transactions listed by relevant industry segment – In Vitro Diagnostics, Medical Devices, and Pharmaceuticals – and then categorized by type – Acquisition, Alliance, or Financing. This month’s column covers deals announced February 2019.
Genentech signed a $2.3bn alliance with Adaptive Biotechnologies around neoantigen-directed T-cell therapies. Two major players in the industry, Bristol-Myers Squibb and Celgene, agreed to combine in a $74bn deal. KKR and Viking Global Investors co-led a nearly $300m investment in genetic disease company BridgeBio Pharma.
At $10.9bn, biopharma financing was at its lowest quarter of the year. GSK’s $5.1bn acquisition of oncology player Tesaro led M&As. And 13 partnerships exceeded the $1bn mark, led by two agreements focused on RNAi.
AC Immune and Eli Lilly teamed up in a $1.9 billion Alzheimer's deal. GSK's focused investment in oncology led to the $5.1 billion acquisition of Tesaro. Biopharma financing totaled $3.1 billion, half of which was from public offerings.
As the pipeline and market for novel cell and gene therapies expands, it is time for drug developers to address other critical aspects in the logistical chain – and for these complex therapies a lot of those issues relate to manufacturing. Looking at specific cases, In Vivo has underlined the main manufacturing challenges facing cell and gene therapy developers, and highlighted methods and approaches being used to generate solutions.