{In Vivo} summarizes the technologies of several medical companies founded within the last year. Confluent Surgical Inc. is developing novel synthetic hydrogels for use as an internal wound dressing and as an embolic agent. FastTrack Systems Inc. aims to improve the time, cost, and quality of clinical trials through its medical informatics technology. Matrix Therapeutics Ltd. was founded to manage the early phase of drug development for products created at the University of Manchester. Principia Pharmaceutical Corp. was launched to develop recombinant albumin-based fusion proteins against cancer, viral diseases and growth deficiencies. Syntonix Pharmaceuticals is focused on the non-invasive delivery of biopharmaceuticals. Tosk Inc. was spun-out of Stanford University to develop animal models and screening systems for the identification of drug candidates based on their in-animal efficacy and safety.