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Cardiovascular Imaging Systems Inc.

Division of Boston Scientific Corp.

Latest From Cardiovascular Imaging Systems Inc.

Ovalis' Reverse Spin

Most small companies grow for a while and then sell off to a larger acquiror. Ovalis, an intriguing start-up in the PFO space, has reversed the process, beginning as part of Abbott Laboratories' Abbott Vascular Division before being spun off as an independent company.

Medical Device Strategy

John Simpson: Reluctant Entrepreneur

John Simpson never set out to be a physician and still does not consider himself a businessman; yet he is a leading interventional cardiologist and has launched more than a half dozen successful device companies. Simpson takes pride in building successful teams, enabling him to delegate the engineering and business responsibilities to others, while focusing on what he does best: figuring out how to better treat the patient. He is perhaps best known for developing over-the-wire angioplasty through his first company, ACS, and has followed that with companies involved with ultrasound (CVIS), atherectomy (DVI and Fox Hollow), vascular closure (Perclose), and chronic total occlusions (LuMend). Simpson remains iconoclastic when it comes to patient care issues. So although angioplasty is where he made his name, he remains suspicious of stents and hopes through his current venture, Fox Hollow, to minimize their use.

Medical Device Business Strategies

FoxHollow: Reviving Atherectomy

The ideal treatment for coronary artery disease is to remove the obstructing plaque, for which several de-bulking technologies, including atherectomy, were developed. The stent revolution of the mid-1990s provided an easier-to-use therapy with more consistent outcomes, relegating de-bulking tools to niche technologies. Physician/entrepreneur John Simpson, who developed the initial atherectomy technology at Devices for Vascular Intervention, remains committed to the principle that it is better to remove plaque than stent it. He believes the next-generation atherectomy device developed at his new company, Fox Hollow, will be a viable treatment option to compete with stenting, including the new generation of drug-eluting stents. Fox Hollow recognizes the need to fight the atherectomy adoption battle on both the ease-of-use and the clinical outcomes fronts, with the latter being particularly important as interventionalists look increasingly to clinical trials in making their product choices. But drug-eluting stent proponents don't believe it is possible to achieve comparable outcomes.

Medical Device Business Strategies

Investing In Life Sciences De Novo

In the last two years, several major venture capital firms that had previously been major investors in life sciences companies abandoned health care for the rarified worlds of information technology and telecommunications. This created a void in health care investing that has seen two venture firms formed recently to focus exclusively on life sciences. First was Versant Ventures (formerly Palladium), which was started in September 1999 by the life sciences partners from Brentwood, IVP and Crosspoint Ventures. And more recently, in February 2000, four veterans of the life science investing wars--John Simpson, MD, Fred Dotzler, Richard Ferrari and David Mauney, MD--got together to form De Novo Ventures, which is also health care-focused. In addition to providing financing, De Novo is also looking to take advantage of the extensive operational experience of its partners by providing start-ups with hands-on management expertise.

BioPharmaceutical Medical Device
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Company Information

  • Industry
  • Medical Devices
  • Therapeutic Areas
  • Alias(es)
  • CVIS
  • Ownership
  • Private
  • Headquarters
  • Worldwide
    • North America
      • USA
  • Parent & Subsidiaries
  • Boston Scientific Corp.
  • Senior Management
  • Richard M Ferrari, Pres. & CEO
    Steve Vandick, VP, Fin. & CFO
    Jack Costello, VP, Sales & Mktg.
    Yue-Teh Jang, VP, R&D
  • Contact Info
  • Cardiovascular Imaging Systems Inc.
    Phone: (408) 749-9088
    595 North Pastoria Avenue
    P.O. Box 3727 Sunnyvale, CA 94086-2916