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NovaScreen Biosciences Corp.

Division of PerkinElmer Inc.

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Solidus Biosciences Inc.

Why are fewer drugs obtaining market approval in recent years? The answer is likely complex, but toxicology issues may be part of the problem. Solidus Biosciences aims to provide pharmaceutical companies with the tools it needs for early stage tox screening. Its MetaChip, short for Metabolizing Enzyme Toxicology Assay chip, is a high through-put biochip capable of screening compounds for their toxicological and metabolic properties in a single test run.
BioPharmaceutical Research and Development Strategies

Combinatorial Biology Begins

Start-ups say they've found ways to create a vast diversity of biological molecules and enzymes--all potential drugs or drug making tools. The trick is transferring genes from microbes that can;t be grown in the lab (some 95% of known species) into onesthat thrive there. Some new firms are collecting microbes from exotic locales. Potential drug company partners are often excited by the idea, but, because little proof exists that the techniques work to create additional diversity, they remain skeptical.
BioPharmaceutical Research and Development Strategies
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