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Ionis Pharmaceuticals, Inc.

http://www.ionispharma.com

Latest From Ionis Pharmaceuticals, Inc.

Kalvista Stops Phase II HAE Prophylactic Trial Following Liver Enzyme Concerns

The US firm’s oral plasma kallikrein inhibitor was associated with liver elevations in a number of Phase II patients, prompting a trial termination and shift in focus to an on-demand program. 

Clinical Trials Rare Diseases

US Supreme Court Preview: ‘Skinny’ Labels, FTC, And FCA – But No Tecfidera As Biogen Loses Bid

Teva’s carve-out fight with GSK over generic Coreg will see the Solicitor General weigh in. Amgen and Juno’s patent petitions remain pending, and the high court stays a Federal Circuit decision invalidating Novartis’ Gilenya patent.

Legal Issues Intellectual Property

Investors Get Selective As China Biotech Funding Rebounds

Oversee returnee-founded Chinese biotech start-ups Nuwacell and Arnatar secure $14m in series A and seed rounds respectively, while four other major deals backed by private equity and venture capital firms raise a combined $116m.

China Financing

AstraZeneca Pulls Plug On Ionis’ PCSK9 Candidate

While the Phase IIb SOLANO trial of ION449 met its primary endpoint, AstraZeneca had set a high bar of 70% LDL cholesterol reduction for competitiveness that the study did not hit.

Clinical Trials Business Strategies
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Company Information

  • Industry
  • Biotechnology
  • Pharmaceuticals
  • Pharmaceuticals
    • Drug Delivery
  • Biotechnology
    • Antisense, Oligonucleotides
    • Drug Discovery Tools
    • Large Molecule
  • Other Names / Subsidiaries
    • Akcea Therapeutics, Inc.
    • Regulus Therapeutics, Inc.
    • Symphony GenIsis, Inc.
    • Isis Pharmaceuticals, Inc.
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