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Genentech options rights to Exelixis' XL518; exercised

Executive Summary

Genentech has signed a deal granting it options to globally develop Exelixis' (small-molecule therapeutics for cancer) XL518, for which Exelixis filed an IND just a few days before the alliance was announced. The candidate inhibits MEK (mitogen-activated protein kinase, MAPK), which plays a major role in the RAS/RAF/MEK/ERK pathway often activated in tumors.

Deal Industry
  • Biotechnology
  • Pharmaceuticals
  • Biotechnology
    • Immuno-Oncology
Deal Status
  • Final
Deal Type
  • Alliance
    • Co-Promotion
    • Includes Contract
    • Includes Royalty or Profit Split Information
    • Intra-Biotech Deal
    • R&D and Marketing (Licensing)
    • Trial Collaborations

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