Start-Up Previews (5/07)
Executive Summary
A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group: In Inflammation, the Indication's the Thing, features profiles of Anthera Pharmaceuticals, Logical Therapeutics, Opsona Therapeutics and VLST Corp.. Plus these Start-Ups Across Health Care: Biodesy, Magenta Medical and NuLens.
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NuLens Ltd.
Today, most of the accommodating and multifocal IOLs that address presbyopia share one thing in common: they are placed, as are the standard lenses used in routine cataract procedures, inside the capsular bag, a thin membrane surrounding the eye's natural lens. It's becoming increasingly apparent that over time, the capsular bag undergoes changes that compromise visual results. NuLens came up with the idea of not using the capsular bag as the housing for the accommodating lens.
Magenta Medical Corp.
Magenta Medical is developing a device that provides hemostasis during minimally-invasive off pump coronary artery bypass graft surgery, without the use of an aortic clamp. Its founder is Dartmouth interventional cardiologist-entrepreneur Aaron Kaplan, whose previous start-ups include LocalMed and Perclose.
Logical Therapeutics Inc.
The gastrointestinal problems linked to NSAIDS are certainly no secret: the ability to mitigate them turned Vioxx into a blockbuster drug, that is, until it was pulled from the market because of cardiovascular problems. Now, Logical Therapeutics in-licensed rights to a pro-drug of naproxen that it thinks will have the GI-safety profile of Vioxx and the cardiovascular safety profile of naproxen.