In Vivo is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By


Angiotech's Life After Drug Eluting Stents

Executive Summary

Angiotech, best known for formulating the paclitaxel that goes on Boston Scientific's drug-eluting stent, has has signed two orthopedics deals; it's acquired NeuColl Inc., a private developer of collagen-based biomaterials for orthopedic applications and has also allied with Orthovita Inc., which will distribute Angiotech's hemostatic biomaterial in orthopedics markets. These, together with a string of other acquisitions in the past year, have diversified Angiotech into interventional cardiology, vascular surgery, anti-adhesion in gynecological surgery, and orthopedics--apparently unrelated fields. That represents a great deal of diversity for a mid-sized company with limited resources, but all of the areas share a common theme. Beyond the drug-eluting stent, Angiotech believes that potentially hundreds of large markets exist where drugs can improve the performance of devices.

You may also be interested in...

World Congress of Cardiology: DES Safety Dominates Discussions

While the greater efficacy of drug-eluting stents (DES) compared to bare-metal stents is widely accepted, over the past year, data has continued to build showing that first-generation DES also have a higher late-stage in-stent thrombosis risk, a complication that can cause death 30% of the time, according to some estimates. The findings of these studies had some physicians at this year's World Congress of Cardiology calling for "an immediate halt to DES overuse." However, most conceded that additional randomized trials will be needed to fully understand the potential risks associated with these devices.

Jumpstart to Products

Discovery research is an ever more difficult investment to justify, so companies are placing greater emphasis on mining discoveries that have already been made but whose real value remains unexploited. Big Pharma, in part inhibited by habit and current infrastructure, has not moved aggressively in the new direction-but the jumpstart model now dominates small-company strategies and will increasingly translate into the rest of the industry.

Executives On The Move: Changes At Exicure, H-Cyte Inc. And More

Recent executive changes in the industry include the appointment of a new Chief Medical Officer at Caribou Biosciences and promotions at Exicure. Meanwhile, H-Cyte Inc., among other companies, has chosen new independent directors.


Related Deals




Ask The Analyst

Ask the Analyst is free for subscribers.  Submit your question and one of our analysts will be in touch.

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts