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Market Intelligence

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Deals In Depth: May 2021

Four $1b+ alliances were penned in May. Topping the list was Bristol-Myers Squibb’s deal with Agenus under which BMS will be granted a global exclusive license to the late-preclinical antibody program AGEN1777 along with a second undisclosed target. Agenus received a $200m up-front payment and could get up to $1.36bn in development, regulatory, and commercialization milestones, plus tiered royalties in the low double-digit to mid-teen range.

Deals Market Intelligence

Deals Shaping The Medical Industry, May 2021

In Vivo's Deal-Making column is a survey of recent health care transactions listed by relevant industry segment – In Vitro Diagnostics, Medical Devices and Pharmaceuticals – and then categorized by type – Acquisition, Alliance, or Financing. This month’s column covers deals announced in May 2021. Data provided by Biomedtracker.

Deals Financing

US FDA’s Most Controversial Drug Approval Decisions, From A To Z

Following accelerated approval of Biogen’s Alzheimer’s drug aducanumab in the US, we look back at 10 of the FDA’s most controversial drug approval decisions, from Addyi to Zohydro.

Approvals Drug Approval Standards

Minimizing Luck In Study Feasibility

Two thirds of clinical trial sites are unable to meet original enrollment goals, with half of sites recruiting either a single patient or failing completely. Study sponsors must scrutinize their approaches to feasibility, as recruitment is such a critical part of overall trial success.

Clinical Trials Market Intelligence

Snapshot: May Highlights

A selection of articles you might have missed from May 2021, including exclusive interviews with industry leaders and a deeper dive into drug development and R&D.

Business Strategies Companies

Deals In Depth: April 2021

Two $1bn+ alliances were penned in April. Vertex and Obsidian entered into an agreement surrounding the discovery of therapies that regulate gene editing for the treatment of serious diseases. Obsidian is eligible for up to $75m in up-front payments and research milestones and could get another $1.3bn in potential milestone payments across up to five potential programs. Artios signed a three-year global research collaboration with Novartis to discover and validate next-generation DNA damage response targets to enhance Novartis’ radioligand therapies. In the top April M&A by deal value, Thermo Fisher and publicly traded contract research organization PPD announced a definitive agreement under which Thermo Fisher will pay $47.50 per share (a 23% premium to the 10-day pre-announcement average) in cash for PPD, for a purchase price of $17.4bn plus the assumption of approximately $3.5bn of net debt. Financing reached $14.6bn in biopharma, $1.2bn in device, and $2.4bn in diagnostics.

Deals Market Intelligence

Deals Shaping The Medical Industry, April 2021

In Vivo's Deal-Making column is a survey of recent health care transactions listed by relevant industry segment – In Vitro Diagnostics, Medical Devices and Pharmaceuticals – and then categorized by type – Acquisition, Alliance, or Financing. This month’s column covers deals announced in April 2021. Data provided by Biomedtracker

Commercial Companies

India’s COVID-19 Nightmare And How Pharma Is Holding Up

A COVID-19 second wave is wreaking havoc in India but pharma appears to be holding things together for now, stretching resources amid a dip in personnel attendance and supply chain strains. Limited vaccine supplies, a spurt in API prices and an inevitable third wave could mean further turbulence ahead.

Asia Pacific India

Dealmaking Quarterly Statistics, Q1 2021

During Q1, biopharma merger and acquisition value reached $34.8bn and drew in $35bn in potential deal value (PDV) from alliances. Device company M&A values reached $10.2bn, while in vitro diagnostic firms and research tools players completed M&A activity that totaled $5bn.

Deals Market Intelligence

Snapshot: April Highlights

A selection of articles you might have missed from April 2021, including exclusive interviews with industry leaders and a deeper dive into drug development and R&D.

Business Strategies Companies

The Shape Of Things To Come: The Value Of Registered Designs In Protecting Medtech Products

As the digital revolution continues to sweep across health care, and the consumer/patient line becomes ever more blurred, healthtech manufacturers are increasingly aware of the need to protect the visual appearance of their products, says legal firm Allen & Overy.  

Business Strategies Commercial

China Cancer Drug Misuse In Spotlight After Shocking Whistleblower Tales

Using PD-1 immuno-oncology drugs to treat post-surgery gastric cancer and prescribing unapproved targeted therapies for colon cancer are just two examples of the apparently widespread misuse of oncology drugs in China, as alleged by an oncologist at a prestigious Peking university hospital.

Asia Pacific China
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