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Start-Up Previews (07/2007)

Executive Summary

A preview of the emerging health care companies profiled in the current, all-profiles issue of Start-Up. This month's profile groups are "Start-Ups in Obesity," "New Technologies for Infertility," and "New Zealand Biotech." Plus these Start-Ups Across Health Care: Intelect Medical, N Spine, and Solace Pharmaceuticals.

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Avandia and the Commercial Impact of FDA's Credibility Gap

GlaxoSmithKline's diabetes drug Avandia survived a perilous FDA advisory committee review. The real question is whether the industry can survive the damage to FDA's credibility.

N Spine Inc.

N Spine Inc. is entering the hot dynamic stabilization market with a second-generation pedicle screw system. The company's technology has the unique ability to elongate and compress, enabling patients' spines to flex and extend in a manner close to natural physiologic movement while at the same time stabilizing shear and axial rotation.

Obecure Ltd.

Israel's Obecure is investigating the potential of a marketed compound, betahistine, in obesity. It's hoping this repositioning approach will both accelerate timelines and help it overcome growing drug safety hurdles.

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