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A Tale Of Two Pipelines

The Promise And Pitfalls Of IO Exuberance And How To Rethink The Approach To Cancer Innovation

Executive Summary

Immuno-oncology has produced some exciting successes, but the field has become intensely crowded. Enormous resources are being poured into duplicative work and shaky hypotheses—overshadowing other pursuits in cancer research while producing limited results. It is time to re-evaluate how the sector should be pursuing innovation in cancer and how it can be smarter in its use of resources—financial investment, talent, bandwidth, patients and data.

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