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Agennix's overall survival in doubt as placebo beats talactoferrin in Ph III NSCLC

This article was originally published in Scrip

Executive Summary

The future of Agennix looks in doubt today after its oral recombinant lactoferrin product talactoferrin alfa failed to improve overall survival in a Phase III study in advanced non-small cell lung cancer (NSCLC) in patients who have received at least two prior therapies. The company's hopes had been riding on a positive outcome of this trial, FORTIS-M, after the drug failed a Phase II/III study in sepsis earlier in the year (scripintelligence.com, 3 February 2012).

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