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Kinetix Pharmaceuticals Inc.

Division of Amgen Inc.
www.kinetixpharm.com

Latest From Kinetix Pharmaceuticals Inc.

Corporate Venture Capital's Complex Agenda

Several forces--rapid technological obsolescence, the impact of information technology on health care, merger integrations, and the need for double digit revenue growth--have caused increasing numbers of large pharmaceutical and medical device companies to create new corporate venture capital groups. But compared to traditional VC firms, whose only goal is to make money for limited partners, corporate VCs have a heavy agenda. They must choose portfolio companies while balancing often-competing goals of strategic benefit and financial return.
BioPharmaceutical Medical Device

Cambridge Drug Discovery Ltd.

Cambridge Drug Discovery was formed in 1997 by four Pfizer scientist who wanted to exploit expertise in assay development, high-throughput screening and informatics, to accelerate the drug discovery process. One of the company's discovery platforms is used to discover small-molecule modulators of G-Protein Coupled Receptors.
BioPharmaceutical

Kindred Spirits in Small Molecule Drug Discovery

Kinetix Pharmaceuticals hoped that a focus on a particular class of targets that shares structural similarities--the protein kinases--would yield small molecules for a variety of therapeutic areas. But in order to realize synergies between multiple research projects in protein kinases, the company couldn't partner the projects out to numerous pharmaceutical partners, each requiring exclusivity and confidentiality. After technological rival Vertex signed a multi-million dollar protein kinase development partnership with Novartis, Kinetix began to rethink its original business model. A $170 million acquisition offer by Amgen Inc. made strategic sense for the start-up.
BioPharmaceutical Research and Development Strategies

Accelerating Small Molecule Drug Discovery

Pharmaceutical companies face two giant risks; compound risk and target risk. So, despite an abundance of so-called validated targets emerging from genomics efforts, and novel high throughput tools for compound synthesis and screening that yield plenty of hits against each target, at the end of the day, pharmaceutical company productivity, as measured by approved drugs, remains low. Recently, several former big-pharma executives have founded private companies that hope to speed up the time it takes to come up with optimized small molecule leads. Each has staked out a particular niche where it thinks it can do better than big pharma at coming up with clinic-ready compounds. Kinetix Pharmaceuticals and Triad Pharmaceuticals hope to leverage their knowledge of particular gene families to come up with optimized leads; Enanta Pharmaceuticals hopes to morph peptides into drugs with a combinatorial approach to binding pharmacophores, and Sunesis hopes to tackle some of the targets that prove intractable for others, or in which only large molecules have been able to intervene. The new small molecule companies share a vision of drug discovery that is based on targets, rather than diseases.
BioPharmaceutical Strategy
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Company Information

  • Industry
  • Biotechnology
  • Pharmaceuticals
  • Therapeutic Areas
  • Alias(es)
  • Ownership
  • Private
  • Headquarters
  • Worldwide
    • North America
      • USA
  • Parent & Subsidiaries
  • Amgen Inc.
  • Senior Management
  • Nicholas Lydon, PhD, Pres. & CEO
    David Armitage, PhD, SVP, R&D
  • Contact Info
  • Kinetix Pharmaceuticals Inc.
    Phone: (781) 391-7577
    200 Boston Ave.
    Medford, MA
    USA
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