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Going Gangbusters on Stroke

This article was originally published in Start Up

Executive Summary

The field of acute ischemic stroke is highly promising but enormously risky and fraught with disappointment. With the exception of tPA, no one has ever demonstrated a pharmaco-mechanism which produces efficacy in the clinic. For now, the key to success for companies will be good efficacy and safety data. Start-ups will need partners, but even alliances with major pharmaceutical companies don’t represent a short-term validation of their efforts, since even big companies are stumbling in this field.

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